Drug resistance is one of the greatest challenges of malaria control programme in Mali. Recent advances in next-generation sequencing (NGS) technologies provide new and effective ways of tracking drug-resistant malaria parasites in Africa.
The diversity and the prevalence of Plasmodium falciparum drug-resistance molecular markers were assessed in Dangassa and Nioro-du-Sahel in Mali, two sites with distinct malaria transmission patterns. Dangassa has an intense seasonal malaria transmission, whereas Nioro-du-Sahel has an unstable and short seasonal malaria transmission.
METHODS
Up to 270 dried blood spot samples (214 in Dangassa and 56 in Nioro-du-Sahel) were collected from P. falciparum positive patients in 2016. Samples were analysed on the Agena MassARRAY® iPLEX platform. Specific codons were targeted in Pfcrt, Pfmdr1, Pfdhfr, and Pfdhps, Pfarps10, Pfferredoxin, Pfexonuclease and Pfmdr2 genes. The Sanger’s 101-SNPs-barcode method was used to assess the genetic diversity of P. falciparum and to determine the parasite species.The Pfcrt_76T chloroquine-resistance genotype was found at a rate of 64.4% in Dangassa and 45.2% in Nioro-du-Sahel (p = 0.025).
The Pfdhfr_51I-59R-108N pyrimethamine-resistance genotype was 14.1% and 19.6%, respectively in Dangassa and Nioro-du-Sahel. Mutations in the Pfdhps_S436-A437-K540-A581-613A sulfadoxine-resistance gene was significantly more prevalent in Dangassa as compared to Nioro-du-Sahel (p = 0.035). Up to 17.8% of the isolates from Dangassa vs 7% from Nioro-du-Sahel harboured at least two codon substitutions in this haplotype. The amodiaquine-resistance Pfmdr1_N86Y mutation was identified in only three samples (two in Dangassa and one in Nioro-du-Sahel).
 Antibody) CD4(EDU-2) Antibody |
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| BNC610345-100 | Biotium | 100uL | EUR 199 |
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Description: Primary antibody against CD4(EDU-2), CF660R conjugate, Concentration: 0.1mg/mL |
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CD4(EDU-2) Antibody |
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| BNC610345-500 | Biotium | 500uL | EUR 544 |
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Description: Primary antibody against CD4(EDU-2), CF660R conjugate, Concentration: 0.1mg/mL |
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CD4(EDU-2) Antibody |
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| BNC680345-100 | Biotium | 100uL | EUR 199 |
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Description: Primary antibody against CD4(EDU-2), CF568 conjugate, Concentration: 0.1mg/mL |
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CD4(EDU-2) Antibody |
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| BNC680345-500 | Biotium | 500uL | EUR 544 |
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Description: Primary antibody against CD4(EDU-2), CF568 conjugate, Concentration: 0.1mg/mL |
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CD4(EDU-2) Antibody |
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| BNC400345-100 | Biotium | 100uL | EUR 199 |
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Description: Primary antibody against CD4(EDU-2), CF640R conjugate, Concentration: 0.1mg/mL |
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CD4(EDU-2) Antibody |
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| BNC400345-500 | Biotium | 500uL | EUR 544 |
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Description: Primary antibody against CD4(EDU-2), CF640R conjugate, Concentration: 0.1mg/mL |
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CD4(EDU-2) Antibody |
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| BNC430345-100 | Biotium | 100uL | EUR 199 |
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Description: Primary antibody against CD4(EDU-2), CF543 conjugate, Concentration: 0.1mg/mL |
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CD4(EDU-2) Antibody |
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| BNC430345-500 | Biotium | 500uL | EUR 544 |
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Description: Primary antibody against CD4(EDU-2), CF543 conjugate, Concentration: 0.1mg/mL |
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CD4(EDU-2) Antibody |
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| BNC550345-100 | Biotium | 100uL | EUR 199 |
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Description: Primary antibody against CD4(EDU-2), CF555 conjugate, Concentration: 0.1mg/mL |
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CD4(EDU-2) Antibody |
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| BNC550345-500 | Biotium | 500uL | EUR 544 |
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Description: Primary antibody against CD4(EDU-2), CF555 conjugate, Concentration: 0.1mg/mL |
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CD4(EDU-2) Antibody |
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| BNC040345-100 | Biotium | 100uL | EUR 199 |
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Description: Primary antibody against CD4(EDU-2), CF405S conjugate, Concentration: 0.1mg/mL |
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CD4(EDU-2) Antibody |
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| BNC040345-500 | Biotium | 500uL | EUR 544 |
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Description: Primary antibody against CD4(EDU-2), CF405S conjugate, Concentration: 0.1mg/mL |
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CD4(EDU-2) Antibody |
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| BNC050345-100 | Biotium | 100uL | EUR 199 |
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Description: Primary antibody against CD4(EDU-2), CF405M conjugate, Concentration: 0.1mg/mL |
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CD4(EDU-2) Antibody |
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| BNC050345-500 | Biotium | 500uL | EUR 544 |
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Description: Primary antibody against CD4(EDU-2), CF405M conjugate, Concentration: 0.1mg/mL |
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CD4(EDU-2) Antibody |
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| BNC470345-100 | Biotium | 100uL | EUR 199 |
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Description: Primary antibody against CD4(EDU-2), CF647 conjugate, Concentration: 0.1mg/mL |
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CD4(EDU-2) Antibody |
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| BNC470345-500 | Biotium | 500uL | EUR 544 |
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Description: Primary antibody against CD4(EDU-2), CF647 conjugate, Concentration: 0.1mg/mL |
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CD4(EDU-2) Antibody |
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| BNUM0345-50 | Biotium | 50uL | EUR 395 |
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Description: Primary antibody against CD4(EDU-2), 1mg/mL |
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CD4(EDU-2) Antibody |
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| BNC700345-100 | Biotium | 100uL | EUR 199 |
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Description: Primary antibody against CD4(EDU-2), CF770 conjugate, Concentration: 0.1mg/mL |
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CD4(EDU-2) Antibody |
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| BNC700345-500 | Biotium | 500uL | EUR 544 |
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Description: Primary antibody against CD4(EDU-2), CF770 conjugate, Concentration: 0.1mg/mL |
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CD4(EDU-2) Antibody |
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| BNC940345-100 | Biotium | 100uL | EUR 199 |
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Description: Primary antibody against CD4(EDU-2), CF594 conjugate, Concentration: 0.1mg/mL |
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CD4(EDU-2) Antibody |
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| BNC940345-500 | Biotium | 500uL | EUR 544 |
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Description: Primary antibody against CD4(EDU-2), CF594 conjugate, Concentration: 0.1mg/mL |
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CD4(EDU-2) Antibody |
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| BNCH0345-100 | Biotium | 100uL | EUR 199 |
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Description: Primary antibody against CD4(EDU-2), Horseradish Peroxidase conjugate, Concentration: 0.1mg/mL |
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CD4(EDU-2) Antibody |
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| BNCH0345-500 | Biotium | 500uL | EUR 544 |
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Description: Primary antibody against CD4(EDU-2), Horseradish Peroxidase conjugate, Concentration: 0.1mg/mL |
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CD4(EDU-2) Antibody |
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| BNC800345-100 | Biotium | 100uL | EUR 199 |
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Description: Primary antibody against CD4(EDU-2), CF680 conjugate, Concentration: 0.1mg/mL |
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CD4(EDU-2) Antibody |
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| BNC800345-500 | Biotium | 500uL | EUR 544 |
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Description: Primary antibody against CD4(EDU-2), CF680 conjugate, Concentration: 0.1mg/mL |
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CD4(EDU-2) Antibody |
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| BNC810345-100 | Biotium | 100uL | EUR 199 |
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Description: Primary antibody against CD4(EDU-2), CF680R conjugate, Concentration: 0.1mg/mL |
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CD4(EDU-2) Antibody |
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| BNC810345-500 | Biotium | 500uL | EUR 544 |
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Description: Primary antibody against CD4(EDU-2), CF680R conjugate, Concentration: 0.1mg/mL |
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CD4(EDU-2) Antibody |
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| BNCP0345-250 | Biotium | 250uL | EUR 383 |
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Description: Primary antibody against CD4(EDU-2), PerCP conjugate, Concentration: 0.1mg/mL |
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CD4(EDU-2) Antibody |
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| BNCR0345-250 | Biotium | 250uL | EUR 383 |
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Description: Primary antibody against CD4(EDU-2), RPE conjugate, Concentration: 0.1mg/mL |
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CD4(EDU-2) Antibody |
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| BNCA0345-250 | Biotium | 250uL | EUR 383 |
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Description: Primary antibody against CD4(EDU-2), APC conjugate, Concentration: 0.1mg/mL |
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CD4(EDU-2) Antibody |
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| BNCAP0345-100 | Biotium | 100uL | EUR 199 |
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Description: Primary antibody against CD4(EDU-2), Alkaline Phosphatase conjugate, Concentration: 0.1mg/mL |
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CD4(EDU-2) Antibody |
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| BNCAP0345-500 | Biotium | 500uL | EUR 544 |
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Description: Primary antibody against CD4(EDU-2), Alkaline Phosphatase conjugate, Concentration: 0.1mg/mL |
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CD4(EDU-2) Antibody |
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| BNCB0345-100 | Biotium | 100uL | EUR 199 |
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Description: Primary antibody against CD4(EDU-2), Biotin conjugate, Concentration: 0.1mg/mL |
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CD4(EDU-2) Antibody |
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| BNCB0345-500 | Biotium | 500uL | EUR 544 |
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Description: Primary antibody against CD4(EDU-2), Biotin conjugate, Concentration: 0.1mg/mL |
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CD4(EDU-2) Antibody |
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| BNC880345-100 | Biotium | 100uL | EUR 199 |
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Description: Primary antibody against CD4(EDU-2), CF488A conjugate, Concentration: 0.1mg/mL |
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CD4(EDU-2) Antibody |
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| BNC880345-500 | Biotium | 500uL | EUR 544 |
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Description: Primary antibody against CD4(EDU-2), CF488A conjugate, Concentration: 0.1mg/mL |
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CD4(EDU-2) Antibody |
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| BNUB0345-100 | Biotium | 100uL | EUR 209 |
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Description: Primary antibody against CD4(EDU-2), Concentration: 0.2mg/mL |
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CD4(EDU-2) Antibody |
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| BNUB0345-500 | Biotium | 500uL | EUR 458 |
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Description: Primary antibody against CD4(EDU-2), Concentration: 0.2mg/mL |
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 Jenner's Stain |
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| GT5545-100G | Glentham Life Sciences | 100 g | EUR 160 |
Jenner's Stain |
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| GT5545-25G | Glentham Life Sciences | 25 g | EUR 81 |
 Giemsa Stain |
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| GT6821-100ML | Glentham Life Sciences | 100 ml | EUR 46 |
Giemsa Stain |
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| GT6821-250ML | Glentham Life Sciences | 250 ml | EUR 59 |
 Wright's stain |
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| GT7819-100G | Glentham Life Sciences | 100 g | EUR 110 |
Wright's stain |
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| GT7819-10G | Glentham Life Sciences | 10 g | EUR 46 |
Wright's stain |
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| GT7819-250G | Glentham Life Sciences | 250 g | EUR 190 |
Wright's stain |
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| GT7819-25G | Glentham Life Sciences | 25 g | EUR 58 |
 Giemsa stain |
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| 20-abx082069 | Abbexa |
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Giemsa stain |
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| 20-abx082518 | Abbexa |
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 DiI Stain |
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| B2742-250 | Biovision | 250 mg | EUR 753 |
DiI Stain |
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| B2742-50 | Biovision | 50 mg | EUR 227 |
Giemsa stain |
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| GB0477 | Bio Basic | 10g | EUR 60.44 |
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 CytoSelect EdU Competitive ELISA Kit |
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| CBA-5101 | Cell Biolabs | 96 assays | EUR 543 |
 Protein Stain-EZ C, Reversible Copper Stain Kit |
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| BSP017 | Bio Basic | 1kit, 10prep | EUR 74.36 |
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 Protein Stain-EZ B, Reversible Zinc Stain Kit |
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| BSP019 | Bio Basic | 1kit, 10prep | EUR 74.36 |
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 Protein Stain-EZG Rapid Coomassie Blue Stain Solution |
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| BSP041 | Bio Basic | 1KIT, 10prep | EUR 76.1 |
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 Silver Stain kit |
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| AR0171 | BosterBio | 1 kit (for 30 assays to stain the gel of 5 X8.5) | EUR 152 |
 ClearSight DNA Stain |
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| BH40501 | Bioatlas | 1ml | EUR 103 |
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Description: For DNA staining and vizualization. |
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 ClearSight RNA Stain |
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| BH40601 | Bioatlas | 400µl | EUR 77 |
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Description: For DNA staining and vizualization. |
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 Reticulum Stain Kit |
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| GRT-1 | ScyTek Laboratories | 1 kit(s) | EUR 255 |
Reticulum Stain Kit |
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| GRT-2 | ScyTek Laboratories | 1 kit(s) | EUR 152 |
 Gram Stain Kit |
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| GSK-1 | ScyTek Laboratories | 125 ml ea. | EUR 125 |
Gram Stain Kit |
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| GSK-2 | ScyTek Laboratories | 30 ml ea. | EUR 92 |
Gram Stain Kit |
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| GSK-500 | ScyTek Laboratories | 500 ml ea. | EUR 303 |
 Jenner's Stain, certified |
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| GT1148-25G | Glentham Life Sciences | 25 g | EUR 107 |
 Giemsa stain, powder |
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| GT7801-100G | Glentham Life Sciences | 100 g | EUR 134 |
Giemsa stain, powder |
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| GT7801-10G | Glentham Life Sciences | 10 g | EUR 46 |
Giemsa stain, powder |
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| GT7801-25G | Glentham Life Sciences | 25 g | EUR 62 |
Giemsa stain, powder |
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| GT7801-50G | Glentham Life Sciences | 50 g | EUR 86 |
Giemsa stain, powder |
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| GT7801-5G | Glentham Life Sciences | 5 g | EUR 42 |
 Fite's Stain Kit |
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| FLS-1 | ScyTek Laboratories | 125 ml ea. | EUR 149 |
Fite's Stain Kit |
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| FLS-500 | ScyTek Laboratories | 500 ml ea. | EUR 295 |
 Iron Stain Kit |
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| IRN-1 | ScyTek Laboratories | 1 kit(s) | EUR 149 |
Iron Stain Kit |
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| IRN-2 | ScyTek Laboratories | 100 Slides | EUR 101 |
Fite's Stain Kit |
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| K1425-125 | Biovision | EUR 370 | |
 Geimsa Stain Kit |
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| K1426-30 | Biovision | EUR 289 | |
Geimsa Stain Kit |
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| K1426-500 | Biovision | EUR 468 | |
 GMS Stain Kit |
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| K1427-125 | Biovision | EUR 446 | |
Gram Stain Kit |
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| k1428-125 | Biovision | EUR 392 | |
Gram Stain Kit |
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| k1428-30 | Biovision | EUR 262 | |
 Orcein Stain Kit |
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| K1432-125 | Biovision | EUR 501 | |
Orcein Stain Kit |
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| K1432-30 | Biovision | EUR 359 | |
 Pneumocystis Stain Kit |
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| K1434-125 | Biovision | EUR 425 | |
Pneumocystis Stain Kit |
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| K1434-30 | Biovision | EUR 316 | |
 Steiner Stain Kit |
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| K1435-125 | Biovision | EUR 446 | |
 Papanicolaou Stain Kit |
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| K1440-30 | Biovision | EUR 207 | |
Papanicolaou Stain Kit |
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| K1440-500 | Biovision | EUR 278 | |
 Copper Stain Kit |
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| CSK-1 | ScyTek Laboratories | 1 kit(s) | EUR 189 |
Copper Stain Kit |
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| CSK-2 | ScyTek Laboratories | 1 kit(s) | EUR 120 |
GMS Stain Kit |
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| KAA-1 | ScyTek Laboratories | 125 ml ea. | EUR 216 |
GMS Stain Kit |
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| KAA-1000 | ScyTek Laboratories | 1000 ml ea. | EUR 884 |
GMS Stain Kit |
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| KAA-500 | ScyTek Laboratories | 500 ml ea. | EUR 523 |
Pneumocystis Stain Kit |
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| PCS-1 | ScyTek Laboratories | 1 kit(s) | EUR 156 |
Pneumocystis Stain Kit |
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| PCS-2 | ScyTek Laboratories | 100 Slides | EUR 104 |
) Trichrome Stain (Blue) |
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| TGB125 | ScyTek Laboratories | 125 ml | EUR 74 |
Trichrome Stain (Blue) |
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| TGB500 | ScyTek Laboratories | 500 ml | EUR 116 |
Trichrome Stain (Blue) |
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| TGB999 | ScyTek Laboratories | 1000 ml | EUR 143 |
 4CN Stain Kit |
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| PW024 | Bio Basic | 5Preps, 5prep | EUR 70.88 |
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 TMB Stain Kit |
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| PW025 | Bio Basic | 5Preps, 5prep | EUR 70.88 |
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, 1 g) EdU (5-ethynyl-2'-deoxyuridine), 1 g |
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| 40540 | lumiprobe | 1 g | EUR 435 |
, 100 mg) EdU (5-ethynyl-2'-deoxyuridine), 100 mg |
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| 10540 | lumiprobe | 100 mg | EUR 112 |
, 500 mg) EdU (5-ethynyl-2'-deoxyuridine), 500 mg |
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| 30540 | lumiprobe | 500 mg | EUR 275 |
, 250 mg) EdU (5-ethynyl-2'-deoxyuridine), 250 mg |
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| 20540 | lumiprobe | 250 mg | EUR 167 |
 Protein Stain-EZ A Ultra Sensitive Coomassie Blue Stain Solution |
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| SK3011 | Bio Basic | 10Minigel, 10UNIT | EUR 66.53 |
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 InstaBlue Protein Stain Solution |
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| B8226-1000 | ApexBio | 1 L | EUR 108 |
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Description: InstaBlue Protein Stain Solution is a ready to use Coomassie protein stain for polyacrylamide gels. Its unique patented mechanism of action stains proteins in 5 minutes while leaving a clear background without the need to fix, wash or destain. |
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InstaBlue Protein Stain Solution |
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| B8226-500 | ApexBio | 500 ml | EUR 84 |
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Description: InstaBlue Protein Stain Solution is a ready to use Coomassie protein stain for polyacrylamide gels. Its unique patented mechanism of action stains proteins in 5 minutes while leaving a clear background without the need to fix, wash or destain. |
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) Bielshowsky's Stain Kit (Modified) |
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| BSK-1 | ScyTek Laboratories | 1 kit(s) | EUR 513 |
 EA-50 Stain Solution |
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| EAC3800 | ScyTek Laboratories | 1 Gal. | EUR 183 |
EA-50 Stain Solution |
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| EAC500 | ScyTek Laboratories | 500 ml | EUR 88 |
EA-50 Stain Solution |
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| EAC999 | ScyTek Laboratories | 1000 ml | EUR 111 |
 EA-65 Stain Solution |
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| EAD3800 | ScyTek Laboratories | 1 Gal. | EUR 154 |
EA-65 Stain Solution |
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| EAD500 | ScyTek Laboratories | 500 ml | EUR 84 |
EA-65 Stain Solution |
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| EAD999 | ScyTek Laboratories | 1000 ml | EUR 101 |
 Giemsa stain, powder, certified |
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| GT5290-100G | Glentham Life Sciences | 100 g | EUR 178 |
Giemsa stain, powder, certified |
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| GT5290-10G | Glentham Life Sciences | 10 g | EUR 62 |
Giemsa stain, powder, certified |
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| GT5290-25G | Glentham Life Sciences | 25 g | EUR 86 |
Giemsa stain, powder, certified |
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| GT5290-50G | Glentham Life Sciences | 50 g | EUR 118 |
Giemsa stain, powder, certified |
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| GT5290-5G | Glentham Life Sciences | 5 g | EUR 50 |
) EvaGreenFluorescent DNA Stain (100µM) |
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| F253 | GeneOn | 1 ml | EUR 121 |
EvaGreenFluorescent DNA Stain (100µM) |
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| F253L | GeneOn | 5x1 ml | EUR 484 |
 Modified Gram Stain Kit |
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| K1429-125 | Biovision | EUR 338 | |
Modified Gram Stain Kit |
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| K1429-30 | Biovision | EUR 251 | |
 Warthin-Starry Stain Kit |
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| K1437-125 | Biovision | EUR 446 | |
 Wright-Giemsa Stain Kit |
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| K1438-30 | Biovision | EUR 262 | |
Wright-Giemsa Stain Kit |
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| K1438-500 | Biovision | EUR 370 | |
 Colloidal Iron Stain Kit |
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| CIK-1 | ScyTek Laboratories | 1 kit(s) | EUR 156 |
Colloidal Iron Stain Kit |
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| CIK-2 | ScyTek Laboratories | 100 Slides | EUR 109 |
 Stain Kit) Papanicolaou (PAP) Stain Kit |
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| PAP-1 | ScyTek Laboratories | 500 ml ea. | EUR 125 |
Papanicolaou (PAP) Stain Kit |
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| PAP-2 | ScyTek Laboratories | 1 kit(s) | EUR 88 |
Papanicolaou (PAP) Stain Kit |
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| PAP-3 | ScyTek Laboratories | 1000 ml ea. | EUR 200 |
 101Bio Ponceau S Stain |
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| P5W4 | 101Bio | NULL | EUR 0 |
) Trichrome Stain Solution (Green) |
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| TGG125 | ScyTek Laboratories | 125 ml | EUR 88 |
Trichrome Stain Solution (Green) |
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| TGG500 | ScyTek Laboratories | 500 ml | EUR 116 |
Trichrome Stain Solution (Green) |
|||
| TGG999 | ScyTek Laboratories | 1000 ml | EUR 143 |
 SensitiveSafe DNA Gel Stain |
|||
| W139-500 | 101Bio | NULL | EUR 0 |
Wright-Giemsa Stain Kit |
|||
| WGK-1 | ScyTek Laboratories | 1 kit(s) | EUR 116 |
Wright-Giemsa Stain Kit |
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| WGK-2 | ScyTek Laboratories | 1 kit(s) | EUR 84 |
Warthin-Starry Stain Kit |
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| WSS-1 | ScyTek Laboratories | 1 kit(s) | EUR 183 |
 India Ink Stain Solution |
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| PW006 | Bio Basic | 100ml | EUR 74.36 |
|
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 Sensitive DAB Stain Kit |
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| PW023 | Bio Basic | 5Preps, 5prep | EUR 69.14 |
|
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 NBT/BCIP Stain Kit |
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| PW032 | Bio Basic | 5Preps, 5prep | EUR 70.88 |
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 INT/BCIP Stain Kit |
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| PW033 | Bio Basic | 5Preps, 5prep | EUR 70.88 |
|
|||
) Amyloid Stain Kit (Congo Red) |
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| AMY-1 | ScyTek Laboratories | 1 kit(s) | EUR 165 |
Amyloid Stain Kit (Congo Red) |
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| AMY-2 | ScyTek Laboratories | 1 kit(s) | EUR 109 |
 Alcian Blue - PAS Stain Kit |
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| APS-1 | ScyTek Laboratories | 1 kit(s) | EUR 205 |
Alcian Blue - PAS Stain Kit |
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| APS-2 | ScyTek Laboratories | 100 Slides | EUR 127 |
 H. Pylori Rapid Stain Kit |
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| AYH-1 | ScyTek Laboratories | 1 kit(s) | EUR 215 |
H. Pylori Rapid Stain Kit |
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| AYH-2 | ScyTek Laboratories | 100 Slides | EUR 132 |
) Reticulum Stain Kit (Modified Gomori's) |
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| GRS-1 | ScyTek Laboratories | 1 kit(s) | EUR 255 |
Reticulum Stain Kit (Modified Gomori's) |
|||
| GRS-2 | ScyTek Laboratories | 100 Slides | EUR 154 |
) Giemsa Stain Kit (May-Grunwald) |
|||
| GMG-1 | ScyTek Laboratories | 1 kit(s) | EUR 173 |
Giemsa Stain Kit (May-Grunwald) |
|||
| GMG-2 | ScyTek Laboratories | 100 Slides | EUR 111 |
 Hematoxylin and Eosin Stain Kit |
|||
| HAE-1 | ScyTek Laboratories | 1 kit(s) | EUR 125 |
Hematoxylin and Eosin Stain Kit |
|||
| HAE-2 | ScyTek Laboratories | 100 Slides | EUR 87 |
) Elastic Stain Kit (Modified Verhoff's) |
|||
| ETS-1 | ScyTek Laboratories | 1 kit(s) | EUR 189 |
Elastic Stain Kit (Modified Verhoff's) |
|||
| ETS-2 | ScyTek Laboratories | 1 kit(s) | EUR 120 |
 Exo-FITC Exosome FACS stain |
|||
| EXOFLOW800A-1 | SBI | 20 reactions | EUR 241 |
|
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 Exo-APC Exosome FACS stain |
|||
| EXOFLOW810A-1 | SBI | 20 reactions | EUR 241 |
|
|||
 SYBR Safe DNA Gel Stain |
|||
| A8743-.5 | ApexBio | 500 ul | EUR 119 |
SYBR Safe DNA Gel Stain |
|||
| A8743-1 | ApexBio | 1 ml | EUR 161 |
SYBR Safe DNA Gel Stain |
|||
| A8743-10 | ApexBio | 10x1 ml | EUR 699 |
SYBR Safe DNA Gel Stain |
|||
| A8743-100 | ApexBio | 100x1 ml | EUR 3390 |
 Maximo-Gel juice fluorescent stain |
|||
| 310012L | GeneOn | 10x10 ml | EUR 1587 |
 LUMITEIN PROTEIN GEL STAIN, 1X |
|||
| 21001 | Biotium | 200mL | EUR 112 |
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Description: Minimum order quantity: 1 unit of 200mL |
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LUMITEIN PROTEIN GEL STAIN, 1X |
|||
| 21001-1 | Biotium | 1L | EUR 226 |
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Description: Minimum order quantity: 1 unit of 1L |
|||
LUMITEIN PROTEIN GEL STAIN, 1X |
|||
| 21001-2 | Biotium | 5L | EUR 802 |
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Description: Minimum order quantity: 1 unit of 5L |
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 LUMITEIN PROTEIN GEL STAIN, 100X |
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| 21002 | Biotium | 2ML | EUR 96 |
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Description: Minimum order quantity: 1 unit of 2ML |
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LUMITEIN PROTEIN GEL STAIN, 100X |
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| 21002-1 | Biotium | 10ML | EUR 178 |
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Description: Minimum order quantity: 1 unit of 10ML |
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LUMITEIN PROTEIN GEL STAIN, 100X |
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| 21002-2 | Biotium | 50ML | EUR 634 |
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Description: Minimum order quantity: 1 unit of 50ML |
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 LipidSpot 488 Lipid Droplet Stain |
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| 70065 | Biotium | 125uL | EUR 401 |
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Description: Minimum order quantity: 1 unit of 125uL |
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LipidSpot 488 Lipid Droplet Stain |
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| 70065-T | Biotium | 20uL | EUR 116 |
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Description: Minimum order quantity: 1 unit of 20uL |
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 LipidSpot 610 Lipid Droplet Stain |
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| 70069 | Biotium | 125uL | EUR 401 |
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Description: Minimum order quantity: 1 unit of 125uL |
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LipidSpot 610 Lipid Droplet Stain |
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| 70069-T | Biotium | 20uL | EUR 114 |
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Description: Minimum order quantity: 1 unit of 20uL |
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 Acid Fast Bacteria Stain Kit |
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| K1424-125 | Biovision | EUR 338 | |
Acid Fast Bacteria Stain Kit |
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| K1424-30 | Biovision | EUR 272 | |
 Modified Southgate's Mucicarmine Stain Kit |
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| K1430-125 | Biovision | EUR 425 | |
Modified Southgate's Mucicarmine Stain Kit |
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| K1430-30 | Biovision | EUR 316 | |
) Differentiating Solution (For Orcein Stain) |
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| DSA125 | ScyTek Laboratories | 125 ml | EUR 71 |
Differentiating Solution (For Orcein Stain) |
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| DSA500 | ScyTek Laboratories | 500 ml | EUR 122 |
 Eosinophil - Mast Cell Stain Kit |
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| CEM-1 | ScyTek Laboratories | 1 kit(s) | EUR 189 |
The lumefantrine-reduced susceptibility Pfmdr1_Y184F mutation was found in 39.9% and 48.2% of samples in Dangassa and Nioro-du-Sahel, respectively. One piperaquine-resistance Exo_E415G mutation was found in Dangassa, while no artemisinin resistance genetic-background were identified. A high P. falciparum diversity was observed, but no clear genetic aggregation was found at either study sites.
Higher multiplicity of infection was observed in Dangassa with both COIL (p = 0.04) and Real McCOIL (p = 0.02) methods relative to Nioro-du-Sahel.This study reveals high prevalence of chloroquine and pyrimethamine-resistance markers as well as high codon substitution rate in the sulfadoxine-resistance gene. High genetic diversity of P. falciparum was observed. These observations suggest that the use of artemisinins is relevant in both Dangassa and Nioro-du-Sahel.